I interrupt the usual stuff of this
blog page to bring serious and vital medical info to the family.
Below are hyperlinks to a couple of
videos regarding the current virus rage and data from physicians.
Next a video from a doctor treating
patients who has discovered soemthingdeviously bad about this
particulart virus ... he does not think the treatment ought focus on
acute respiratory disease syndrome using higher pressure ventilator
process, and he hints at why:
https://www.youtube.com/watch?v=1EWQPgF6-UQ&feature=youtu.be
And finally a laymen's explanation for
the astonishing deviousness of this particular virus, as in the
following:
Copied from an article that appeared
on the website "Medium" but which was deleted by "Medium."
Covid-19 had us all fooled, but now we might have finally
found its secret. libertymavenstock libertymavenstock Follow
Apr 4 · 8 min read
In the last 3–5 days, a mountain of anecdotal evidence
has come out of NYC, Italy, Spain, etc. about COVID-19 and
characteristics of patients who get seriously ill. It’s not only
piling up but now leading to a general field-level consensus backed
up by a few previously little-known studies that we’ve had it all
wrong the whole time. Well, a few had some things eerily correct
(cough Trump cough), especially with Hydroxychloroquine with
Azithromicin, but we’ll get to that in a minute.
There is no ‘pneumonia’ nor ARDS. At least not the
ARDS with established treatment protocols and procedures we’re
familiar with. Ventilators are not only the wrong solution, but high
pressure intubation can actually wind up causing more damage than
without, not to mention complications from tracheal scarring and
ulcers given the duration of intubation often required… They may
still have a use in the immediate future for patients too far to
bring back with this newfound knowledge, but moving forward a new
treatment protocol needs to be established so we stop treating
patients for the wrong disease.
The past 48 hours or so have seen a huge revelation:
COVID-19 causes prolonged and progressive hypoxia (starving your body
of oxygen) by binding to the heme groups in hemoglobin in your red
blood cells. People are simply desaturating (losing o2 in their
blood), and that’s what eventually leads to organ failures that
kill them, not any form of ARDS or pneumonia. All the damage to the
lungs you see in CT scans are from the release of oxidative iron from
the hemes, this overwhelms the natural defenses against pulmonary
oxidative stress and causes that nice, always-bilateral ground glass
opacity in the lungs. Patients returning for re-hospitalization days
or weeks after recovery suffering from apparent delayed post-hypoxic
leukoencephalopathy strengthen the notion COVID-19 patients are
suffering from hypoxia despite no signs of respiratory ‘tire out’
or fatigue.
Here’s the breakdown of the whole process, including
some ELI5-level cliff notes. Much has been simplified just to keep it
digestible and layman-friendly.
Your red blood cells carry oxygen from your lungs to all
your organs and the rest of your body. Red blood cells can do this
thanks to hemoglobin, which is a protein consisting of four “hemes”.
Hemes have a special kind of iron ion, which is normally quite toxic
in its free form, locked away in its center with a porphyrin acting
as it’s ‘container’. In this way, the iron ion can be ‘caged’
and carried around safely by the hemoglobin, but used to bind to
oxygen when it gets to your lungs.
When the red blood cell gets to the alveoli, or the
little sacs in your lungs where all the gas exchange happens, that
special little iron ion can flip between FE2+ and FE3+ states with
electron exchange and bond to some oxygen, then it goes off on its
little merry way to deliver o2 elsewhere. Here’s where COVID-19
comes in. Its glycoproteins bond to the heme, and in doing so that
special and toxic oxidative iron ion is “disassociated”
(released). It’s basically let out of the cage and now freely
roaming around on its own. This is bad for two reasons:
1) Without the iron ion, hemoglobin can no longer bind to
oxygen. Once all the hemoglobin is impaired, the red blood cell is
essentially turned into a Freightliner truck cab with no trailer and
no ability to store its cargo.. it is useless and just running around
with COVID-19 virus attached to its porphyrin. All these useless
trucks running around not delivering oxygen is what starts to lead to
desaturation, or watching the patient’s spo2 levels drop. It is
INCORRECT to assume traditional ARDS and in doing so, you’re
treating the WRONG DISEASE. Think of it a lot like carbon monoxide
poisoning, in which CO is bound to the hemoglobin, making it unable
to carry oxygen. In those cases, ventilators aren’t treating the
root cause; the patient’s lungs aren’t ‘tiring out’, they’re
pumping just fine. The red blood cells just can’t carry o2, end of
story. Only in this case, unlike CO poisoning in which eventually the
CO can break off, the affected hemoglobin is permanently stripped of
its ability to carry o2 because it has lost its iron ion. The body
compensates for this lack of o2 carrying capacity and deliveries by
having your kidneys release hormones like erythropoietin, which tell
your bone marrow factories to ramp up production on new red blood
cells with freshly made and fully functioning hemoglobin. This is the
reason you find elevated hemoglobin and decreased blood oxygen
saturation as one of the 3 primary indicators of whether the shit is
about to hit the fan for a particular patient or not.
2) That little iron ion, along with millions of its
friends released from other hemes, are now floating through your
blood freely. As I mentioned before, this type of iron ion is highly
reactive and causes oxidative damage. It turns out that this happens
to a limited extent naturally in our bodies and we have cleanup &
defense mechanisms to keep the balance. The lungs, in particular,
have 3 primary defenses to maintain “iron homeostasis”, 2 of
which are in the alveoli, those little sacs in your lungs we talked
about earlier. The first of the two are little macrophages that roam
around and scavenge up any free radicals like this oxidative iron.
The second is a lining on the walls (called the epithelial surface)
which has a thin layer of fluid packed with high levels of
antioxidant molecules.. things like abscorbic acid (AKA Vitamin C)
among others. Well, this is usually good enough for naturally
occurring rogue iron ions but with COVID-19 running rampant your body
is now basically like a progressive state letting out all the
prisoners out of the prisons… it’s just too much iron and it
begins to overwhelm your lungs’ countermeasures, and thus begins
the process of pulmonary oxidative stress. This leads to damage and
inflammation, which leads to all that nasty stuff and damage you see
in CT scans of COVID-19 patient lungs. Ever noticed how it’s always
bilateral? (both lungs at the same time) Pneumonia rarely ever does
that, but COVID-19 does… EVERY. SINGLE. TIME.
— — — — — — — — — — — — – Once
your body is now running out of control, with all your oxygen trucks
running around without any freight, and tons of this toxic form of
iron floating around in your bloodstream, other defenses kick in.
While your lungs are busy with all this oxidative stress they can’t
handle, and your organs are being starved of o2 without their
constant stream of deliveries from red blood cell’s hemoglobin, and
your liver is attempting to do its best to remove the iron and store
it in its ‘iron vault’. Only its getting overwhelmed too. It’s
starved for oxygen and fighting a losing battle from all your
hemoglobin letting its iron free, and starts crying out “help, I’m
taking damage!” by releasing an enzyme called alanine
aminotransferase (ALT). BOOM, there is your second of 3 primary
indicators of whether the shit is about to hit the fan for a
particular patient or not.
Eventually, if the patient’s immune system doesn’t
fight off the virus in time before their blood oxygen saturation
drops too low, ventilator or no ventilator, organs start shutting
down. No fuel, no work. The only way to even try to keep them going
is max oxygen, even a hyperbaric chamber if one is available on 100%
oxygen at multiple atmospheres of pressure, just to give what’s
left of their functioning hemoglobin a chance to carry enough o2 to
the organs and keep them alive. Yeah we don’t have nearly enough of
those chambers, so some fresh red blood cells with normal hemoglobin
in the form of a transfusion will have to do. The core point being,
treating patients with the iron ions stripped from their hemoglobin
(rendering it abnormally nonfunctional) with ventilator intubation is
futile, unless you’re just hoping the patient’s immune system
will work its magic in time. The root of the illness needs to be
addressed.
Best case scenario? Treatment regimen early, before
symptoms progress too far. Hydroxychloroquine (more on that in a
minute, I promise) with Azithromicin has shown fantastic, albeit
critics keep mentioning ‘anecdotal’ to describe the mountain,
promise and I’ll explain why it does so well next. But forget
straight-up plasma with antibodies, that might work early but if the
patient is too far gone they’ll need more. They’ll need all the
blood: antibodies and red blood cells. No help in sending over a
detachment of ammunition to a soldier already unconscious and
bleeding out on the battlefield, you need to send that ammo along
with some hemoglobin-stimulant-magic so that he can wake up and fire
those shots at the enemy.
The story with Hydroxychloroquine All that hilariously
misguided and counterproductive criticism the media piled on
chloroquine (purely for political reasons) as a viable treatment will
now go down as the biggest Fake News blunder to rule them all. The
media actively engaged their activism to fight ‘bad orange man’
at the cost of thousands of lives. Shame on them. How does
chloroquine work? Same way as it does for malaria. You see, malaria
is this little parasite that enters the red blood cells and starts
eating hemoglobin as its food source. The reason chloroquine works
for malaria is the same reason it works for COVID-19 — while not
fully understood, it is suspected to bind to DNA and interfere with
the ability to work magic on hemoglobin. The same mechanism that
stops malaria from getting its hands on hemoglobin and gobbling it up
seems to do the same to COVID-19 (essentially little snippets of DNA
in an envelope) from binding to it. On top of that,
Hydroxychloroquine (an advanced descendant of regular old
chloroquine) lowers the pH which can interfere with the replication
of the virus. Again, while the full details are not known, the entire
premise of this potentially ‘game changing’ treatment is to
prevent hemoglobin from being interfered with, whether due to malaria
or COVID-19.
No longer can the media and armchair pseudo-physicians
sit in their little ivory towers, proclaiming “DUR so stoopid,
malaria is bacteria, COVID-19 is virus, anti-bacteria drug no work on
virus!”. They never got the memo that a drug doesn’t need to
directly act on the pathogen to be effective. Sometimes it’s enough
just to stop it from doing what it does to hemoglobin, regardless of
the means it uses to do so.
Anyway, enough of the rant. What’s the end result here?
First, the ventilator emergency needs to be re-examined. If you’re
putting a patient on a ventilator because they’re going into a coma
and need mechanical breathing to stay alive, okay we get it. Give ’em
time for their immune systems to pull through. But if they’re
conscious, alert, compliant — keep them on O2. Max it if you have
to. If you HAVE to inevitably ventilate, do it at low pressure but
max O2. Don’t tear up their lungs with max PEEP, you’re doing
more harm to the patient because you’re treating the wrong disease.
Ideally, some form of treatment needs to happen to:
Inhibit viral growth and replication. Here plays CHQ+ZPAK+ZINC or
other retroviral therapies being studies. Less virus, less hemoglobin
losing its iron, less severity and damage.
Therapies used for anyone with abnormal hemoglobin or
malfunctioning red blood cells. Blood transfusions. Whatever, I don’t
know the full breadth and scope because I’m not a physician. But
think along those lines, and treat the real disease. If you’re
thinking about giving them plasma with antibodies, maybe if they’re
already in bad shape think again and give them BLOOD with antibodies,
or at least blood followed by plasma with antibodies. Now that we
know more about how this virus works and affects our bodies, a whole
range of options should open up. Don’t trust China. China is
ASSHOE. (disclaimer: not talking about the people, just talking about
the regime). They covered this up and have caused all kinds of death
and carnage, both literal and economic. The ripples of this pandemic
will be felt for decades. Fini.
